ECF impairment is common

Impairment of Methotrexate Transport Is Common in Osteosarcoma Tumor Samples

Osteosarcoma does not respond well to conventional dose methotrexate but does respond to high-dose methotrexate. Previous work has indicated that this resistance may be due to impaired transport of methotrexate across the cell membrane. In this study, the PT430 competitive displacement assay was adapted to evaluate methotrexate transport in 69 high-grade osteosarcoma tumor samples. All samples ...

Hearing impairment is common among Saami adults in Northern Finland

The Saami are the only indigenous population in Europe and their traditional living area is northern Scandinavia. Hearing impairment (HI) among Saami has not been studied before. The objective was to investigate the presence and type of HI among Saami adults, aged 49-77 years (median age 61 years), living in northern Finland. In addition, the presence of self-reported hearing difficulties, diff...

ECF - Event Correlation for Forensics

The focus of the research described in this paper is on the nature of the event information provided in commonly available computer and other logs and the extent to which it is possible to correlate such event information despite its heterogeneous nature and origins. The strategic purpose of the research has been to develop a means by which a consolidated repository of such information can be c...

Page 2 ST - ECF Newsletter

Pain in ehlers-danlos syndrome is common, severe, and associated with functional impairment.

CONTEXT The Ehlers-Danlos Syndrome (EDS) is a clinically and genetically heterogeneous group of heritable connective tissue disorders characterized by joint hypermobility, skin hyperextensibility, and tissue fragility. Musculoskeletal pain is mentioned in the diagnostic criteria and described as early in onset, chronic, and debilitating. However, systematic research on pain in EDS is scarce. ...